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Immune self and non-sense

John McKellar Stewart

pp. 105-122

This chapter presents two rival paradigms in immunology, a field where the theme "Sense and Non-sense" has particular relevance. According to classical immunology, the immune system can potentially perceive everything; and it triggers the destruction of everything that it actually perceives. Consequently, in order to avoid self-destruction, this sort of immune system perceives everything except its own body. The alterna- tive paradigm is based on autopoiesis: What we see — Is not what we see - But what we are. This chapter presents computer simulations based on a mathematical model of an idiotypic network, which involves morpho- genesis in shape-space. The choice between these two paradigms involves value-judgments; this reflexively poses the theme of sense-making at a higher-level of abstraction.

Publication details

DOI: 10.1057/9781137363367_5

Full citation:

Stewart, J.M. (2014)., Immune self and non-sense, in M. Cappuccio & T. Froese (eds.), Enactive cognition at the edge of sense-making, Dordrecht, Springer, pp. 105-122.

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